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Porins let drugs in, efflux pumps kick them out — alone, neither does much damage.
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📊 Working through ROC-AUC from scratch, then poking at its blind spots — low prevalence, calibration, and finally Decision Curve Analysis.
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Textbooks say LOOCV has the lowest bias but highest variance compared to 10 and 5-fold.
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🧬 Back to basics!
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Exploring the CovR/S two-component system in Group A Strep 🧫 — from genome annotation with Bakta & BaktFold, to AlphaFold confidence metrics, and a first attempt at protein docking with Haddock3.
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A note to myself on survival analysis — KM curves, log-rank tests & Cox models 🧮 If I wrote it the way I understood it, maybe I’ll actually remember it 🤞 Motivations We see survival analysis or more generally called time-to-event analysis almost all the t…
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Dipping my toes into quantum computing 🌊 — circuits, gates, superposition.
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🦠 Made up my own memory tricks — Gatekeeper, Dumpster, Repressor — to understand AmpC mechanics.
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📊 Dipping my toes into financial statements — income, balance sheet & cash flow.
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Exploring pip/tazo PTA for Pseudomonas using popPK simulation.
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🧪 Diving into PK/PD for the first time — simulating ceftriaxone with mrgsolve in R.