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I have always wanted to understand how a cell works.
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It’s done.
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At the start of my PhD, I was faced with what seemed like a mountain to climb: build, largely alone, a foundation model for single-cell RNA-seq data.
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To start the VCC, you need to know a few things.
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A year and a half in.
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In my recent paper scPRINT I define the term Large Cell Model but what are they?
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Ancestry Bias in CRISPR Screens 🎉 Thrilled to share our paper on ancestry biases in CRISPR screens published in Nature Communications!
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Managing GRNs and What They Mean In my recent paper scPRINT, I went into a deep dive on gene regulatory networks.
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When analysing a classification task for my recent paper scPRINT, I fell into a fascinating “data-sciency” rabbit-hole about AUPRC, AUC and AP.
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Bioinformatician’s main tool for discovery has often been differential expression analysis.