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Curcumin is a constituent (up to ∼5%) of the traditional medicine known as turmeric.
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Chemical standardization, along with morphological and DNA analysis ensures the authenticity and advances the integrity evaluation of botanical preparations.
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Centrifugal partition chromatography (CPC) and all countercurrent separation apparatus provide chemists with efficient ways to work with complex matrixes, especially in the domain of natural products.
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Abstract from conference NAPRALERT is a database on natural products, including data on ethnobotany, chemistry, pharmacology, toxicology, and clinical trials from literature dating back to the 19th century.
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The notion of data transparency is gaining a strong awareness among the scientific community.
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NAPRALERT is a database on natural products, including data on the ethnobotany, chemistry, pharmacology, toxicology, and clinical trials.
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Composite-based, tooth colored dental restorations, in spite of their aesthetic appeal, are limited by a short life span.
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I made some new stuff on this project.
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Using magit-status each time or having to type the commands was boring.
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Today I had to automate changing some IDs in Protege.
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Today I received an alert from my work email about a mailbox too full.
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To test the ESP, the Arduino system is good enough.
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I wanted to make a fretless guitar like Vigier of Ron Thal.
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How to connect the ESP8266 and how to communicate with the default non-free firmware to test the device.
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I just received my ESP8266-12F from Electrodragon.
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Dereplication represents a key step for rapidly identifying known secondary metabolites in complex biological matrices.
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The revision of the structure of the sesquiterpene aquatolide from a bicyclo[2.2.0]hexane to a bicyclo[2.1.1]hexane structure using compelling NMR data, X-ray crystallography, and the recent confirmation via full synthesis exemplify that the achievement of
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Tonight, I played with git hooks.
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High-throughput biology has contributed a wealth of data on chemicals, including natural products (NPs).
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Plant derived proanthocyanidins are well-established compounds exhibiting high dentin biomodification potency.
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The ability of certain oligomeric proanthocyanidins (OPACs) to enhance the biomechanical properties of dentin involves collagen cross-linking of the 1.3–4.5 nm wide space via protein–polyphenol interactions.
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A recent article by Baell(1) on the problems experienced by medicinal chemists with pan-assay interference compounds (PAINS) and Shoichet’s work(2) on the impact of aggregation occurring in high throughput screening libraries, prompts a consideration of h…
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C-glycosylated flavones, including orientin, isoorientin, vitexin, and isovitexin, are minor but biologically significant constituents of fruit extracts of the chaste-tree (Vitex agnus-castus L.), a botanical supplement used to treat PMS and postmenopausal
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The acquisition of 1D 1H NMR (HNMR) spectra is one of earliest steps in characterizing natural products and other organic molecules.
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1D NMR spectra contain a wealth of vital structural information that can enhance the description of bioactive molecules.
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This article is in english, but the original one is in french.
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Proanthocyanidins (PACs) are secondary plant metabolites that mediate nonenzymatic collagen cross-linking and enhance the properties of collagen based tissue, such as dentin.
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The polyphenol source and molecular structure complexity affects interactions of proanthocyanidins (PACs) with dentin matrix.
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Stilbenoids have received increasing attention over the last two decades since the discovery of resveratrol in wine.
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Dimeric stilbene glucosides 1–3 [two diastereomers of (−)-gnemonoside A (1a and 1b), (−)-gnemonoside C (2), and (−)-gnemonoside D (3)] as well as a mixture of the two enantiomers of gnetin C (4) were isolated from the rhizomes of Gnetum africanum.
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The present study demonstrates the importance of adequate precision when reporting the δ and J parameters of frequency domain 1H NMR (HNMR) data.
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I use Notmuch to manage my emails (and that’s just wonderfully fast) and use the Emacs frontend for it.
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Grapevine canes are rich in resveratrol and its complex derivatives.
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Microglia-driven inflammatory processes are thought to play an important role in ageing and several neurological disorders.
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Suite à l’émission de France Inter « Sur les épaules de Darwin, La forme des mots », j’ai décidé d’expérimenter un peu avec la conversion d’images en sons par transformée inverse de fourier.
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Wine is a major dietary source of numerous potentially health promoting stilbenoids that have been the subject of many qualitative and quantitative studies.
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Flavours extracted from oak wood during barrel ageing contribute to the organoleptic character of wines and spirits.
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We present stilbenoid profiles of canes from 16 grapevines.
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The interaction between Vitis vinifera and trunk disease fungi requires better understanding.
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Countercurrent chromatography techniques are increasingly used in the fractionation and purification steps of natural products due to their excellent versatility and efficiency.
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The phytochemical study of the root extract of the stilbenoid-rich Vitis riparia × Vitis berlandieri grapevine was carried out by centrifugal partition chromatography (CPC).