Bjonnh.net

Over the past two decades, quantitative structure–activity relationship (QSAR) modeling has evolved substantially, driven by improved data accessibility, open-source descriptor generation, mature machine learning libraries, and scalable cloud computing.

I made a tiny device that uses pressure from my mouth to control MIDI.

A simple right-click menu option to launch containerized Jupyter notebooks in any directory.

Natural products (NPs) continue to inform the discovery and development of a diversity of drugs, both marketed and investigational.

This exploratory study was designed to identify factors implicating microbial influence on medicinal plant metabolomes.

I’m organizing a MIDI workshop at PumpingStation One sometime in 2024.

A small (28x21mm) MIDI board for your microcontroller projects.

DINOctopus is a 10 ports small device made that can merge/split/mix MIDI signals and act as a USB interface.

A class on Open Source based FPGA programming at the local hackerspace.

Phytochemical investigation of Marsypopetalum modestum (Annonaceae) led to the isolation of a new phenylpropanoid glycoside, lyciumphenylpropanoid B (10), along with nine known compounds (1-9) from an aqueous methanolic extract of the stem.

The Akai MPC One is a nice device, but it is a pain to backup if you have to get the SDCard out everytime.

Lotus search Lotus search is a tool to search for compounds and taxa in the Lotus database.

An evaluation of select medicinal species from Chapter 5 was performed by exploring the global scientific literature for evidence in support of the folkloric uses, through convergence in bioactivity profiles or corroboration of therapeutic uses.

On using 3d printer screens and controllers for your own projects.

FauxDIS is an educational resource loosely inspired from the FBI’s CODIS database.

I recently got a WD SN850.

Contemporary bioinformatic and chemoinformatic capabilities hold promise to reshape knowledge management, analysis and interpretation of data in natural products research.

Two new diprenylated coumaric acid isomers (1a and 1b) and two known congeners, capillartemisin A (2) and B (3), were isolated from Artemisia scoparia as bioactive markers using bioactivity-guided HPLC fractionation.

Curcuma longa (turmeric) has an extensive history of ethnomedical use for common ailments, and “curcumin”-containing dietary supplements (CDS) are a highly visible portion of today’s self-medication market.

I finally put my hands on a Trinket M0 for the Trackpoint.

A friend of mine Pierre Grangé-Praderas needed to make a webpage with graphs.

I spent a day adding a trackPoint to my keyboard to avoid having to move all the time to the trackball.

This Perspective of the published essential medicinal chemistry of cannabidiol (CBD) provides evidence that the popularization of CBD-fortified or CBD-labeled health products and CBD-associated health claims lacks a rigorous scientific foundation.

In a continuing search for neuroprotective stilbenoids, two uncommon diastereomeric stilbenoid glucosides, africanoside A (1) and B (2) as well as fifteen known stilbenes, E-resveratrol, E-gnetifolin E, E-piceid, E-resveratroloside, E-gnetifolin K, E-gnet…

Chlorophylls are present in all extracts from the aerial parts of green plant materials.

Finally, I am trying to reorganize this website, add a portfolio and other kind of stuff that will help me remember the ton of stuff I wrote but never talked about.

During my PhD, I was working with devices that help separating components of mixtures and devices to analyze these components.

CENAPT Navigator is a compilation of resources related to Natural Product Research and Pharmacognosy.

This website has been made with Hugo and a custom theme that involves a lot of css, html, templates.

NAPRALERT is a leading database containing >40 years of the natural products literature.

Whereas generic, LC-based pharmaceutical control quality procedures depend largely on the detection mode and can be particularly ‘blind’ to certain impurities, NMR is a more versatile and, thus, often more judicious detector.

Mass spectrometry (MS) offers unrivalled sensitivity for the metabolite profiling of complex biological matrices encountered in natural products (NP) research.

Took me some time to learn how SNMP v3 (and SNMP in general) works.

Ensuring identity, purity, and reproducibility are equally essential during synthetic chemistry, drug discovery, and for pharmaceutical product safety.

When using docker in LXD/LXC, the FS performance is really really bad.

I needed to run Docker in LXC containers on my Ubuntu servers.

I’m now a heavy user of Draw.io a great piece of Free software from jgraph.

I’m moving all my old file-based ssh and gpg keys to a YubiKey 4 hardware key.

With contributions from the global natural product (NP) research community, and continuing the Raw Data Initiative, this review collects a comprehensive demonstration of the immense scientific value of disseminating raw nuclear magnetic resonance (NMR) da…

[Draft published as is, this is old.]

I was complaining on IRC about someone sending me a screenshot as a word file.

Humans have co-evolved alongside numerous other organisms, some having a profound effect on health and nutrition.

How to update the PERC6/i firmware from Linux.

We had this conference in Chicago in 2016.

We had [this conference](https://gfp.people.uic.edu/ccc2016/) in Chicago in 2016.

This is an answer to some reactions to our review article on Curcumin.