Liam Kaufman

The drug development tool pathway was added to the FDA act, however, key provisions of the 21st Century cure act are set to expire in September 2026 including what looks like funding for this program.

I was recently discussing the FDA’s Drug Development Tool (DDT) qualification program with a colleague.

Last week the FDA released a draft guidance on the use of AI to support regulatory decision-making for drugs.

An important consideration for the development of new drugs is whether they can be abused - the FDA released a guidance document in January 2017 - detailing considerations in the assessment of abuse potential for drugs.

From 2023 to 2024 Us Against Alzheimer’s published a number of publications and abstracts covering their “Alzheimer’s Disease Patient and Caregiver Engagement (AD PACE)” What Matters Most (WMM) research program.

With more and more digital health drug development tools (DDT) being used in clinical research I’m increasingly interested in understanding how we can differentiate these tools from status quo “gold standard” measures.

Today the FDA held their “Digital Health Advisory Committee Meeting” to get feedback from industry experts (payers, providers, startups, etc), academics and clinicians on “Generative Artificial Intelligence-Enabled Mental Health Medical Devices.”

This week the UK Government unveiled the results of an AI pilot that they conducted with Microsoft 365 Copilot.

Github uses Linguist, a Ruby library, to help detect which programming language is in a given file.

In a previous article I explored ng-repeat, it's implementation, and how to create a custom repeater.

In my previous article I discussed the benefits of using dependency injection to make code more testable and modular.

Over the past 6 years I’ve used Ruby on Rails, Backbone.js, Node and AngularJS.

My first impression of Angular.js was one of amazement.

After rewriting Understoodit several times I’ve spent a lot of time thinking about building real-time web applications.

You’ve created an app that your beta testers use and your launch was a huge success.

Last Week: Before Launching, Build Software People Use You’ve created a product that people want to use, and now you’re eager to launch.

You’re a talented developer and have a great idea for a startup.

Being nice to your customers seems like a no brainer.

I was among many Canadian developers who where happy to hear that Stripe had come to Canada.

With the rise of thick client-side applications, and Node.js, JavaScript has become an increasingly important programming language.

UPDATE: Based on the feedback in the comments (Phineas), I've added an index to the comments table and updated the results.

There are several popular modules for adding password-based user authentication to an Express.js app.

Over the years traffic to Hacker News (HN), "a social news website about computer hacking and startup companies" (Wikipedia), has grown consistently, with an average of 150,000 daily uniques.

Dustin Curtis, the creator of Svbtle, recently mentioned on Twitter: I miss the Hacker News from four years ago.

I always found it odd that accessing DOM elements with Ruby, or Python, wasn't as easy as it was with jQuery.

In the last few years there has been a proliferation of noSQL databases.

UPDATE: see my new article on adding real-time to your Rails application.

Despite making several small Backbone.js apps in the past year, Backbone.js had never really clicked with me.

Recently I've been working with both the HTML 5 File API and Socket.IO and it occured to me that those technologies could be used to send, and push, files between the client and server.

I’m currently in the midst of creating an application that utilizes Socket.IO for real-time communication between users.

With the public release of ember.js, I excitedly poured over the examples hoping to find a framework that would make Creating, Reading, Updating and Deleting (CRUD) easier.

I want to master JavaScript.

After 3 years without change, I've redone my personal website using Jekyll and Bootstrap.

In an effort to add some personality to this site I thought I'd list my favourite songs. iTunes provides a mechanism for users to rate songs, by giving a song 0 to 5 stars.